Research peptide
IGF-1 LR3
1 mg
Select size
$74.50CAD
Volume pricing
- Buy 2Save 5%$141.55 ($70.78 each)
- Buy 3Save 10%$201.15 ($67.05 each)
Applies to the total quantity in your cart.
Research material
Supplied in a sealed glass vial and labelled with a batch reference. Batch-specific documentation is available on request. For Research Use Only. Not for Human or Animal Use.
- Presentation
- 1 mg
- Container
- Sealed glass vial
- Batch reference
- Printed on every unit
- Documentation
- Batch-specific COA on request
- Research use
- For Research Use Only
Description
IGF-1 LR3 (Long R3 IGF-1) is a modified analogue of insulin-like growth factor-1 (IGF-1) engineered to alter its interaction with IGF-binding proteins and extend its biological activity compared with native IGF-1. The molecule incorporates an amino-acid substitution at position 3 and an additional 13-amino-acid extension at the N-terminus, creating a 83-amino-acid analogue.
IGF-1 is a central component of the growth hormone (GH) / IGF-1 axis, playing an important role in cellular growth, differentiation, protein synthesis, and tissue development. IGF-1 LR3 is therefore of research interest as a model for investigating IGF-1 receptor signaling and downstream anabolic and metabolic pathways.
The modified structure is particularly relevant to studies examining reduced IGF-binding-protein interaction, receptor-mediated signaling, cellular proliferation, differentiation, glucose metabolism, and tissue-growth pathways. Research also includes skeletal muscle biology, connective-tissue models, and mechanisms governing cellular growth and repair.
Key Research Areas:
- IGF-1 receptor signaling
- GH / IGF-1 axis research
- Cellular growth and differentiation
- Protein synthesis and anabolic signaling
- Skeletal muscle and tissue biology
- Glucose and metabolic signaling
- Cell proliferation and survival pathways
- Connective-tissue and regenerative biology
Why IGF-1 LR3?
Compared with native IGF-1, the LR3 modification is designed to reduce binding to IGF-binding proteins, resulting in a substantially different pharmacological profile and longer biological activity in experimental systems. This makes IGF-1 LR3 a useful research analogue for investigating sustained IGF-1 receptor signaling and the biological consequences of prolonged IGF-axis activation.
Importantly, IGF-1 LR3 is an investigational research analogue and is not equivalent to an approved therapeutic formulation of recombinant human IGF-1. Findings from experimental models should not be interpreted as evidence of established clinical benefits.
At Kinetus Biolabs, IGF-1 LR3 is positioned as an investigational IGF-1 analogue for researchers studying growth-factor signaling, IGF-1 receptor biology, cellular growth, metabolic regulation, and the broader GH/IGF-1 axis.
Kinetus Biolabs | Precision Science. Peak Potential.
Research Use Only — Not for Human Consumption.
